Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) is a naturally occurring tetrapeptide present in the human body, primarily known as a physiological inhibitor of hematopoiesis. Beyond its role in regulating the proliferation of hematopoietic stem cells, it exhibits significant anti-inflammatory, anti-fibrotic, and organ-protective properties, particularly in the cardiovascular system and kidneys.