Calcium Alpha-Ketoglutarate (Ca-AKG) is a stable, bioavailable calcium salt of alpha-ketoglutarate (AKG)-a key intermediate in the Krebs cycle, which drives cellular energy production. It serves as a critical metabolic fuel and scavenger, playing an essential role in amino acid synthesis and mitochondrial function. Ca-AKG has gained significant attention for its potential anti-aging and healthspan-extending effects, as it supports cellular energetics, promotes collagen synthesis, and enhances protein balance. Additionally, it acts as a precursor to glutamate and glutamine, making it relevant for neurotransmitter metabolism and gut health. Its calcium-bound form improves stability and absorption, making it a preferred supplement form in clinical and longevity research.
