LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It plays a critical role in innate immunity by exhibiting broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Beyond its direct antimicrobial effects, LL-37 functions as an immunomodulatory peptide, regulating inflammation, promoting wound healing, and enhancing tissue repair. It is expressed in various epithelial cells and immune cells, making it a key player in the body's first line of defense against infection and injury.
