Nobiletin is a naturally occurring flavonoid compound found primarily in citrus fruits, especially in the peels of oranges and tangerines. It belongs to the subclass of polymethoxyflavones, which are known for their strong antioxidant and anti-inflammatory properties. Research has shown that nobiletin exhibits a wide range of biological activities, including neuroprotective, anticancer, and cardioprotective effects. It has also been studied for its potential to regulate circadian rhythms and improve metabolic disorders such as obesity and diabetes. Due to its excellent bioavailability and safety profile, nobiletin has become a promising candidate for functional foods and therapeutic applications.
